The Indiana State Department of Health (ISDH) is working with local health departments in southern Indiana to respond to a recent increase in hepatitis A cases, many of which are tied to a large outbreak in Kentucky. In the last month, 17 cases of hepatitis A have been confirmed statewide, including 11 in Clark and Floyd counties. Since Jan. 1, ISDH has confirmed 40 cases of hepatitis A statewide. Typically, fewer than 20 cases are confirmed each year in Indiana. Many of the southern Indiana cases have involved inmates in the Clark County Jail. However, an elementary school in Clark County and a Bob Evans restaurant on State Street in New Albany also have been impacted. For a complete list of populations that might be at higher risk for hepatitis A, visit the Centers for Disease Control and Prevention (CDC) website at https://www.cdc.gov/hepatitis/hav/havfaq.htm#general. Additional information can be found at https://www.cdc.gov/hepatitis/hav/afaq.htm.