Yesterday at around 5am, all lanes of the west bound Indiana Toll Road I-80/90 at the 39 mile marker (this is directly under U.S. 421) were closed after to crash. All west bound traffic was diverted off at exit 49 (LaPorte exit). Preliminary information is that a semi that was south bound on US 421 left the roadway for unknown reasons, went down the embankment onto I-80/90 into west bound traffic where it hit a pick-up pulling a trailer. The incident was described as not life threatening. A large amount of oil and diesel fuel was spilled.